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Acetylation of GATA-1 is required for chromatin occupancy
All 3 hematopoietic GATA transcription factors, GATA-1, GATA-2, and GATA-3, are acetylated, although the in vivo role of this modification remains unclear. We examined the functions of an acetylation-defective mutant of GATA-1 in maturing erythroid cells. We found that removal of the acetylation sit...
Guardat en:
| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society of Hematology
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895476/ https://ncbi.nlm.nih.gov/pubmed/16888089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-032847 |
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