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Acetylation of GATA-1 is required for chromatin occupancy

All 3 hematopoietic GATA transcription factors, GATA-1, GATA-2, and GATA-3, are acetylated, although the in vivo role of this modification remains unclear. We examined the functions of an acetylation-defective mutant of GATA-1 in maturing erythroid cells. We found that removal of the acetylation sit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lamonica, Janine M., Vakoc, Christopher R., Blobel, Gerd A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society of Hematology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895476/
https://ncbi.nlm.nih.gov/pubmed/16888089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-032847
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