The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice

Plasminogen (Plg)–deficient mice experience wasting and have decreased longevity due to disseminated fibrin deposition. We generated mice with combined deficiencies of Plg and coagulation factor IX (fIX) or XI (fXI) to determine the effects on the Plg null phenotype. Mice lacking Plg and fIX (Plg(–/...

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Detalhes bibliográficos
Main Authors: Cheng, Qiufang, Zhao, Yong, Lawson, William E., Polosukhin, Vasiliy V., Johnson, Joyce E., Blackwell, Timothy S., Gailani, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895339/
https://ncbi.nlm.nih.gov/pubmed/15985536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0577
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