Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an αIIbβ3- and aggregation-independent manner

Binding of von Willebrand factor (VWF) to the platelet membrane glycoprotein (GP) Ib-IX-V complex initiates a signaling cascade that causes αIIbβ3 activation and platelet aggregation. Previous work demonstrated that botrocetin (bt)/VWF–mediated agglutination activates αIIbβ3 and elicits adenosine tr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Junling, Pestina, Tamara I., Berndt, Michael C., Jackson, Carl W., Gartner, T. Kent
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895306/
https://ncbi.nlm.nih.gov/pubmed/15985541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1667
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados