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Inhibition of APC anticoagulant activity on oxidized phospholipid by anti–β(2)-glycoprotein I monoclonal antibodies

Activated protein C (APC) anticoagulant activity and the ability to be inhibited by auto-antibodies associated with thrombosis are strongly augmented by the presence of phosphatidylethanolamine (PE) and phospholipid oxidation. β(2)-glycoprotein I (β(2)-GPI) is a major antigen for antiphospholipid an...

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Bibliografiske detaljer
Main Authors: Safa, Omid, Esmon, Charles T., Esmon, Naomi L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895229/
https://ncbi.nlm.nih.gov/pubmed/15890686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0404
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