Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and β(2)-glycoprotein I (β(2)-GPI) on apoptotic cells

The ability of an anti-phospholipid (LJ1) and an anti-β(2)-GPI (RSP-57) human MoAb to bind to apoptotic but not viable cells was demonstrated in this study. Both MoAbs were derived from patients with systemic lupus erythematosus and anti-phospholipid antibody syndrome. The parallel analysis of the s...

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Hauptverfasser: Pittoni, V, Ravirajan, C T, Donohoe, S, Machin, S J, Lydyard, P M, Isenberg, D A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2000
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905581/
https://ncbi.nlm.nih.gov/pubmed/10691928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01161.x
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