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Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

Honokiol (HNK) is an active component purified from magnolia, a plant used in traditional Chinese and Japanese medicine. Here we show that HNK significantly induces cytotoxicity in human multiple myeloma (MM) cell lines and tumor cells from patients with relapsed refractory MM. Neither coculture wit...

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書誌詳細
主要な著者: Ishitsuka, Kenji, Hideshima, Teru, Hamasaki, Makoto, Raje, Noopur, Kumar, Shaji, Hideshima, Hiromasa, Shiraishi, Norihiko, Yasui, Hiroshi, Roccaro, Aldo M., Richardson, Paul, Podar, Klaus, Le Gouill, Steven, Chauhan, Dharminder, Tamura, Kazuo, Arbiser, Jack, Anderson, Kenneth C.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society of Hematology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895215/
https://ncbi.nlm.nih.gov/pubmed/15870175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0346
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