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Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype

Homozygous loss of function of Runx1 (Runt-related transcription factor 1 gene) during murine development results in an embryonic lethal phenotype characterized by a complete lack of definitive hematopoiesis. In light of recent reports of disparate requirements for hematopoietic transcription factor...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Growney, Joseph D., Shigematsu, Hirokazu, Li, Zhe, Lee, Benjamin H., Adelsperger, Jennifer, Rowan, Rebecca, Curley, David P., Kutok, Jeffery L., Akashi, Koichi, Williams, Ifor R., Speck, Nancy A., Gilliland, D. Gary
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society of Hematology 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895175/
https://ncbi.nlm.nih.gov/pubmed/15784726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-3280
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