Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

Although Notch receptor expression on malignant B cells is widespread, the effect of Notch signaling in these cells is poorly understood. To investigate Notch signaling in B-cell malignancy, we assayed the effect of Notch activation in multiple murine and human B-cell tumors, representing both immat...

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Detalhes bibliográficos
Main Authors: Zweidler-McKay, Patrick A., He, Yiping, Xu, Lanwei, Rodriguez, Carlos G., Karnell, Fredrick G., Carpenter, Andrea C., Aster, Jon C., Allman, David, Pear, Warren S.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895093/
https://ncbi.nlm.nih.gov/pubmed/16118316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0355
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