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Potential approach to immunotherapy of chronic lymphocytic leukemia (CLL): enhanced immunogenicity of CLL cells via infection with vectors encoding for multiple costimulatory molecules
Chronic lymphocytic leukemia (CLL) is a disease of CD5(+) B lymphocytes (designated as CLL cells) that are inefficient antigen-presenting cells. Their poor ability to present antigens to the T cells, largely due to an inadequate costimulatory capacity, is manifested as a failure to stimulate prolife...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
© 2005 by The American Society of Hematology
2005
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895050/ https://ncbi.nlm.nih.gov/pubmed/16081691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1214 |
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