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Chronic Lymphocytic Leukemia (CLL) Cells Genetically Modified to Express B7-1, ICAM-1, and LFA-3 Confer APC Capacity to T Cells from CLL Patients
In chronic lymphocytic leukemia (CLL), malignant B cells and nonmalignant T cells exhibit dysfunction. We previously demonstrated that infection of CLL cells with modified vaccinia Ankara (MVA) expressing the costimulatory molecules B7-1, ICAM-1, and LFA-3 (designated TRICOM) increased expression of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664396/ https://ncbi.nlm.nih.gov/pubmed/19009294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0611-5 |
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