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An inducible caspase 9 safety switch for T-cell therapy
The efficacy of adoptive T-cell therapy as treatment for malignancies may be enhanced by genetic modification of infused cells. However, oncogenic events due to vector/transgene integration, and toxicities due to the infused cells themselves, have tempered enthusiasm. A safe and efficient means of r...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
© 2005 by The American Society of Hematology
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895037/ https://ncbi.nlm.nih.gov/pubmed/15728125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4564 |
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