A carregar...
Thrombin-catalyzed activation of factor VIII with His substituted for Arg372 at the P(1) site
Thrombin-catalyzed proteolysis at Arg372 of factor VIII is essential for procofactor activation. However, hemophilia A patients with the missense mutation Arg372 to His possess a mild to moderate phenotype yet show no detectable cleavage at this bond. To evaluate this discrepancy, we prepared and st...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
© 2005 by The American Society of Hematology
2005
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895030/ https://ncbi.nlm.nih.gov/pubmed/15705787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-10-3939 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|