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A classification system for cross-reactive material-negative factor XI deficiency

The bleeding disorder associated with factor XI (fXI) deficiency is typically inherited as an autosomal recessive trait. However, some fXI mutations may be associated with dominant disease transmission. FXI is a homodimer, a feature that could allow certain mutations to exert a dominant-negative eff...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kravtsov, Dmitri V., Monahan, Paul E., Gailani, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895004/
https://ncbi.nlm.nih.gov/pubmed/15728123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-05-1864
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