Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group.

A previous study (M.J. Robinson, B.A. Martin, T.D. Gootz, P.R. McGuirk, M. Moynihan, J.A. Sutcliffe, and N. Osheroff, J. Biol. Chem. 266:14585-14592, 1991) demonstrated that novel 6,8-difluoroquinolones were potent effectors of eukaryotic topoisomerase II. To determine the contribution of the C-8 fl...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Robinson, M J, Martin, B A, Gootz, T D, McGuirk, P R, Osheroff, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.4.751
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