Loading...

Proofreading and Secondary Structure Processing Determine the Orientation Dependence of CAG·CTG Trinucleotide Repeat Instability in Escherichia coli

Expanded CAG·CTG trinucleotide repeat tracts are associated with several human inherited diseases, including Huntington's disease, myotonic dystrophy, and spinocerebellar ataxias. Here we describe a new model system to investigate repeat instability in the Escherichia coli chromosome. Using thi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zahra, Rabaab, Blackwood, John K., Sales, Jill, Leach, David R. F.
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2007 by the Genetics Society of America 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893049/
https://ncbi.nlm.nih.gov/pubmed/17339223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.069724
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!