Nalaganje...

Proofreading and Secondary Structure Processing Determine the Orientation Dependence of CAG·CTG Trinucleotide Repeat Instability in Escherichia coli

Expanded CAG·CTG trinucleotide repeat tracts are associated with several human inherited diseases, including Huntington's disease, myotonic dystrophy, and spinocerebellar ataxias. Here we describe a new model system to investigate repeat instability in the Escherichia coli chromosome. Using thi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Zahra, Rabaab, Blackwood, John K., Sales, Jill, Leach, David R. F.
Format: Artigo
Jezik:Inglês
Izdano: Copyright © 2007 by the Genetics Society of America 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893049/
https://ncbi.nlm.nih.gov/pubmed/17339223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.069724
Oznake: Označite
Brez oznak, prvi označite!