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Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1

Ribonucleotide reductase maintains cellular deoxyribonucleotide pools and is thus tightly regulated during the cell cycle to ensure high fidelity in DNA replication. The Sml1 protein inhibits ribonucleotide reductase activity by binding to the R1 subunit. At the completion of each turnover cycle, th...

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Detalhes bibliográficos
Main Authors: Zhang, Zhen, Yang, Kui, Chen, Chin-Chuan, Feser, Jason, Huang, Mingxia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892911/
https://ncbi.nlm.nih.gov/pubmed/17277086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611095104
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