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Structure of testis ACE glycosylation mutants and evidence for conserved domain movement

Human angiotensin-converting enzyme is an important drug target for which little structural information has been available until recent years. The slow progress in obtaining a crystal structure was due to the problem of surface glycosylation, a difficulty that has thus far been overcome by the use o...

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Bibliografiske detaljer
Main Authors: Watermeyer, Jean M., Sewell, B. Trevor, Schwager, Sylva L., Natesh, Ramanathan, Corradi, Hazel R., Acharya, K. Ravi, Sturrock, Edward D.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892614/
https://ncbi.nlm.nih.gov/pubmed/17042482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061146z
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