PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1

Mutations in the PTEN induced putative kinase 1 (PINK1) gene cause an autosomal recessive form of Parkinson disease (PD). So far, no substrates of PINK1 have been reported, and the mechanism by which PINK1 mutations lead to neurodegeneration is unknown. Here we report the identification of TNF recep...

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Bibliografiska uppgifter
Huvudupphovsmän: Pridgeon, Julia W, Olzmann, James A, Chin, Lih-Shen, Li, Lian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2007
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892574/
https://ncbi.nlm.nih.gov/pubmed/17579517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050172
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