BAG5 Protects against Mitochondrial Oxidative Damage through Regulating PINK1 Degradation

Mutations in PTEN-induced kinase 1 (PINK1) gene cause PARK6 familial Parkinsonism, and loss of the stability of PINK1 may also contribute to sporadic Parkinson's disease (PD). Degradation of PINK1 occurs predominantly through the ubiquitin proteasome system (UPS), however, to date, few of the p...

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Detalhes bibliográficos
Main Authors: Wang, Xuejing, Guo, Jifeng, Fei, Erkang, Mu, Yingfeng, He, Shuang, Che, Xiangqian, Tan, Jieqiong, Xia, Kun, Zhang, Zhuohua, Wang, Guanghui, Tang, Beisha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901670/
https://ncbi.nlm.nih.gov/pubmed/24475098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086276
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