PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

Cells keep their energy balance and avoid oxidative stress by regulating mitochondrial movement, distribution, and clearance. We report here that two Parkinson’s disease proteins, the Ser/Thr-kinase PINK1 and ubiquitin-ligase Parkin, participate in this regulation by arresting mitochondrial movement...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Xinnan, Winter, Dominic, Ashrafi, Ghazaleh, Schlehe, Julia, Wong, Yao Liang, Selkoe, Dennis, Rice, Sarah, Steen, Judith, LaVoie, Matthew J., Schwarz, Thomas L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261796/
https://ncbi.nlm.nih.gov/pubmed/22078885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.018
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