The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro.

Benzer Materyaller

• (-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.
  Yazar:: Coates, J A, ve diğerleri
  Baskı/Yayın Bilgisi: (1992)
• Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog.
  Yazar:: Soudeyns, H, ve diğerleri
  Baskı/Yayın Bilgisi: (1991)
• Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
  Yazar:: Schinazi, R F, ve diğerleri
  Baskı/Yayın Bilgisi: (1992)
• Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma.
  Yazar:: Hart, G J, ve diğerleri
  Baskı/Yayın Bilgisi: (1992)
• High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase.
  Yazar:: Boucher, C A, ve diğerleri
  Baskı/Yayın Bilgisi: (1993)