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Essential Roles for Angiotensin Receptor AT1a in Bleomycin-Induced Apoptosis and Lung Fibrosis in Mice

Apoptosis of alveolar epithelial cells (AECs) has been implicated as a key event in the pathogenesis of lung fibrosis. Recent studies demonstrated a role for the synthesis and binding of angiotensin II to receptor AT1 in the induction of AEC apoptosis by bleomycin (BLEO) and other proapoptotic stimu...

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Библиографические подробности
Главные авторы: Li, Xiaopeng, Rayford, Heather, Uhal, Bruce D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892377/
https://ncbi.nlm.nih.gov/pubmed/14633624
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