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Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis

Earlier work from this laboratory showed that local generation of angiotensin (ANG) II is required for the pathogenesis of experimental pulmonary fibrosis and that ANG peptides are expressed robustly in the lungs of patients with idiopathic pulmonary fibrosis (IPF). Angiotensin converting enzyme-2 (...

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Detalhes bibliográficos
Main Authors: Li, Xiaopeng, Molina-Molina, Maria, Abdul-Hafez, Amal, Uhal, Victor, Xaubet, Antonio, Uhal, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494775/
https://ncbi.nlm.nih.gov/pubmed/18441099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00009.2008
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