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Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts
BACKGROUND: Angiotensin (ANG) II is involved in experimental hyperoxia-induced lung fibrosis. Angiotensin-converting enzyme-2 (ACE-2) degrades ANG II and is thus protective, but is downregulated in adult human and experimental lung fibrosis. Hyperoxia is a known cause of chronic fibrotic lung diseas...
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| 發表在: | Pediatr Res |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group US
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119454/ https://ncbi.nlm.nih.gov/pubmed/25665060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2015.27 |
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