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Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts

BACKGROUND: Angiotensin (ANG) II is involved in experimental hyperoxia-induced lung fibrosis. Angiotensin-converting enzyme-2 (ACE-2) degrades ANG II and is thus protective, but is downregulated in adult human and experimental lung fibrosis. Hyperoxia is a known cause of chronic fibrotic lung diseas...

詳細記述

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書誌詳細
出版年:Pediatr Res
主要な著者: Oarhe, Chinyere I., Dang, Vinh, Dang, MyTrang, Nguyen, Hang, Gopallawa, Indiwari, Gewolb, Ira H., Uhal, Bruce D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group US 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119454/
https://ncbi.nlm.nih.gov/pubmed/25665060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2015.27
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