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Angiotensin-(1–7)/mas inhibits apoptosis in alveolar epithelial cells through upregulation of MAP kinase phosphatase-2

Earlier work from this laboratory showed that autocrine generation of angiotensin II and c-Jun-NH(2)-terminal kinase phosphorylation (p-JNK) are both required events in alveolar epithelial cell (AEC) apoptosis. Although earlier data showed that angiotensin-(1–7) [ANG-(1–7)] protects against AEC apop...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Gopallawa, Indiwari, Uhal, Bruce D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888557/
https://ncbi.nlm.nih.gov/pubmed/26637635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00187.2015
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