Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1–7/Mas axis

Earlier work from this laboratory demonstrated that apoptosis of alveolar epithelial cells (AECs) requires autocrine generation of angiotensin (ANG) II. More recent studies showed that angiotensin converting enzyme-2 (ACE-2), which degrades ANGII to form ANG1–7, is protective but severely downregula...

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Bibliografiska uppgifter
Huvudupphovsmän: Uhal, Bruce D., Li, Xiaopeng, Xue, Anita, Gao, Xu, Abdul-Hafez, Amal
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
Ämnen:
Editorial Focus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174737/
https://ncbi.nlm.nih.gov/pubmed/21665960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00222.2010
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