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Role of E-selectin in bleomycin induced lung fibrosis in mice

BACKGROUND—Bleomycin (BLM), a well known anti-cancer drug, often causes acute lung injury and fibrosis by mechanisms that are not well understood. It is suspected that some proteases and active oxygen species generated from inflammatory cells cause the lung injury and subsequent lung fibrosis. It wa...

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Autors principals: Azuma, A., Takahashi, S., Nose, M., Araki, K., Araki, M., Takahashi, T., Hirose, M., Kawashima, H., Miyasaka, M., Kudoh, S.
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1745688/
https://ncbi.nlm.nih.gov/pubmed/10639534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.55.2.147
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