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Allelic Loss Is Often the First Hit in the Biallelic Inactivation of the p53 and DPC4 Genes During Pancreatic Carcinogenesis

The presumed precursor lesions of pancreatic ductal adenocarcinoma were recently classified according to their increasing grade of dysplasia and were designated as pancreatic intraepithelial neoplasia (PanIN) 1 through 3. In this study, we tested whether molecular genetic alterations can be correlat...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lüttges, Jutta, Galehdari, Hamid, Bröcker, Verena, Schwarte-Waldhoff, Irmgard, Henne-Bruns, Doris, Klöppel, Günter, Schmiegel, Wolff, Hahn, Stephan A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2001
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891939/
https://ncbi.nlm.nih.gov/pubmed/11337365
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