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The selection of acceptable protein mutations
We have determined the general constraints that govern sequence divergence in proteins that retain entirely, or very largely, the same structure and function. To do this we collected data from three different groups of orthologous sequences: those found in humans and mice, in humans and chickens, an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1891269/ https://ncbi.nlm.nih.gov/pubmed/17540730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703737104 |
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