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The selection of acceptable protein mutations

We have determined the general constraints that govern sequence divergence in proteins that retain entirely, or very largely, the same structure and function. To do this we collected data from three different groups of orthologous sequences: those found in humans and mice, in humans and chickens, an...

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Detaylı Bibliyografya
Asıl Yazarlar: Sasidharan, Rajkumar, Chothia, Cyrus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891269/
https://ncbi.nlm.nih.gov/pubmed/17540730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703737104
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