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Fatal hemorrhage in mice lacking γ-glutamyl carboxylase

The carboxylation of glutamic acid residues to γ-carboxyglutamic acid (Gla) by the vitamin K–dependent γ-glutamyl carboxylase (γ-carboxylase) is an essential posttranslational modification required for the biological activity of a number of proteins, including proteins involved in blood coagulation...

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Detalhes bibliográficos
Main Authors: Zhu, Aihua, Sun, Hongmin, Raymond, Richard M., Furie, Barbara C., Furie, Bruce, Bronstein, Mila, Kaufman, Randal J., Westrick, Randal, Ginsburg, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890832/
https://ncbi.nlm.nih.gov/pubmed/17327402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-064188
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