Φορτώνει......
Ligand density dramatically affects integrin αIIbβ3-mediated platelet signaling and spreading
The impact of ligand density on integrin-mediated cell adhesion and outside-in signaling is not well understood. Using total internal reflection fluorescent microscopy, conformation-specific antibodies, and Ca(2+) flux measurements, we found that the surface density of fibrinogen affects αIIbβ3-medi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society of Hematology
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890822/ https://ncbi.nlm.nih.gov/pubmed/17332246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-054015 |
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