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Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription.

Hepadnaviruses replicate by reverse transcription of an RNA intermediate within subviral core particles in the cytoplasm of infected hepatocytes. Recognition of the epsilon encapsidation signal located on the 5' end of the pregenomic RNA by the viral polymerase occurs early in core particle assembly...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Fallows, D A, Goff, S P
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3067-3073.1995
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