Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription.
Hepadnaviruses replicate by reverse transcription of an RNA intermediate within subviral core particles in the cytoplasm of infected hepatocytes. Recognition of the epsilon encapsidation signal located on the 5' end of the pregenomic RNA by the viral polymerase occurs early in core particle assembly...
Saved in:
| Published in: | J Virol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1995
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3067-3073.1995 |
| Tags: |
No Tags, Be the first to tag this record!
|