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Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription.

Hepadnaviruses replicate by reverse transcription of an RNA intermediate within subviral core particles in the cytoplasm of infected hepatocytes. Recognition of the epsilon encapsidation signal located on the 5' end of the pregenomic RNA by the viral polymerase occurs early in core particle assembly...

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Udgivet i:J Virol
Principais autores: Fallows, D A, Goff, S P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3067-3073.1995
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