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Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

Down syndrome (DS) is the most common genetic disorder associated with mental retardation (MR). It is believed that many of the phenotypic features of DS stem from enhanced expression of a set of genes located within the triplicated region on chromosome 21. Among those genes is DYRK1A encoding dual...

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Bibliografski detalji
Glavni autori: Dowjat, Wieslaw K., Adayev, Tatyana, Kuchna, Izabela, Nowicki, Krzysztof, Palminiello, Sonia, Hwang, Yu Wen, Wegiel, Jerzy
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890010/
https://ncbi.nlm.nih.gov/pubmed/17145134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2006.11.02
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