An etoposide-induced block in vaccinia virus telomere resolution is dependent on the virus-encoded DNA ligase.
Etoposide, an inhibitor of the breakage-reunion reaction associated with cellular type II DNA topoisomerases, was shown to inhibit plaque formation of vaccinia virus. This drug had a major effect on the segregation of newly replicated DNA concatemers. Gene expression and the initiation and elongatio...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
|---|---|
| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1995
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2082-2091.1995 |
| الوسوم: |
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