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Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme.

The N-terminal 60 kDa (amino acids 1 to 545) of the D1 subunit of vaccinia virus mRNA capping enzyme is an autonomous bifunctional domain with triphosphatase and guanylyltransferase activities. We previously described two alanine cluster mutations, R77 to A (R77A)-K79A and E192A-E194A, which selecti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, L, Martins, A, Deng, L, Shuman, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC230301/
https://ncbi.nlm.nih.gov/pubmed/9371657
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