An etoposide-induced block in vaccinia virus telomere resolution is dependent on the virus-encoded DNA ligase.

Etoposide, an inhibitor of the breakage-reunion reaction associated with cellular type II DNA topoisomerases, was shown to inhibit plaque formation of vaccinia virus. This drug had a major effect on the segregation of newly replicated DNA concatemers. Gene expression and the initiation and elongatio...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	DeLange, A M, Carpenter, M S, Choy, J, Newsway, V E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2082-2091.1995
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