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Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

The ubiquitin-related modifier SUMO regulates a wide range of cellular processes by post-translational modification with one, or a chain of SUMO molecules. Sumoylation is achieved by the sequential action of several enzymes in which the E2, Ubc9, transfers SUMO from the E1 to the target mostly with...

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Main Authors: Knipscheer, Puck, van Dijk, Willem J, Olsen, Jesper V, Mann, Matthias, Sixma, Titia K
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888673/
https://ncbi.nlm.nih.gov/pubmed/17491593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601711
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