Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

Infection by murine retroviruses in embryonic carcinoma (EC) and embryonic stem cells is highly restricted. The transcriptional unit of the Moloney murine leukemic virus (MoMuLV) long terminal repeat (LTR) is inactive in EC and embryonic stem cells in association with increased proviral methylation....

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Challita, P M, Skelton, D, el-Khoueiry, A, Yu, X J, Weinberg, K, Kohn, D B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.748-755.1995
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!