Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells

Retroviral vectors based on the Moloney murine leukemia virus (MoMuLV) have shown inconsistent levels and duration of expression as well as a propensity for the acquisition of de novo methylation in vivo. MoMuLV-based vectors are known to contain sequences that are capable of suppressing or preventi...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Robbins, Paul B., Skelton, Dianne C., Yu, Xiao-Jin, Halene, Stephanie, Leonard, Earl H., Kohn, Donald B.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1998
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.10182
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