Transduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture.

Genetic modification of hematopoietic stem cells with a synthetic "anti-human immunodeficiency virus type 1 (HIV-1) gene" which inhibits replication of HIV-1 may allow production of mature lymphoid and monocytic cells resistant to HIV-1 growth after autologous transplantation. Because productive HIV...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bahner, I, Kearns, K, Hao, Q L, Smogorzewska, E M, Kohn, D B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4352-4360.1996
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