Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

Infection by murine retroviruses in embryonic carcinoma (EC) and embryonic stem cells is highly restricted. The transcriptional unit of the Moloney murine leukemic virus (MoMuLV) long terminal repeat (LTR) is inactive in EC and embryonic stem cells in association with increased proviral methylation....

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Challita, P M, Skelton, D, el-Khoueiry, A, Yu, X J, Weinberg, K, Kohn, D B
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.748-755.1995
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!