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RADICAL SITES IN M. TUBERCULOSIS KATG IDENTIFIED USING EPR SPECTROSCOPY, THE 3-D CRYSTAL STRUCTURE AND ELECTRON-TRANSFER COUPLINGS
Catalase-peroxidase (KatG) from Mycobacterium tuberculosis, a Class I peroxidase, exhibits high catalase activity and peroxidase activity with various substrates, and is responsible for activation of the commonly used antitubercular drug, isoniazid (INH). KatG readily forms amino acid based radicals...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885898/ https://ncbi.nlm.nih.gov/pubmed/17204474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607309200 |
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