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Iron Overload and Heart Fibrosis in Mice Deficient for Both β2-Microglobulin and Rag1
Genetic causes of hereditary hemochromatosis (HH) include mutations in the HFE gene, a β2-microglobulin (β2m)-associated major histocompatibility complex class I-like protein. Accordingly, mutant β2m(−/−) mice have increased intestinal iron absorption and develop parenchymal iron overload in the liv...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Investigative Pathology
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885749/ https://ncbi.nlm.nih.gov/pubmed/11106561 |
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