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Widespread Nitration of Pathological Inclusions in Neurodegenerative Synucleinopathies

Reactive nitrogen species may play a mechanistic role in neurodegenerative diseases by posttranslationally altering normal brain proteins. In support of this hypothesis, we demonstrate that an anti-3-nitrotyrosine polyclonal antibody stains all of the major hallmark lesions of synucleinopathies incl...

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主要な著者: Duda, John E., Giasson, Benoit I., Chen, Qiping, Gur, Tamar L., Hurtig, Howard I., Stern, Matthew B., Gollomp, Steven M., Ischiropoulos, Harry, Lee, Virginia M.-Y., Trojanowski, John Q.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885725/
https://ncbi.nlm.nih.gov/pubmed/11073803
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