Convergence of Heat Shock Protein 90 with Ubiquitin in Filamentous α-Synuclein Inclusions of α-Synucleinopathies

Heat shock proteins (Hsps) facilitate refolding of denatured polypeptides, but there is limited understanding about their roles in neurodegenerative diseases characterized by misfolded proteins. Because Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy are α-synucleino...

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Detalhes bibliográficos
Main Authors: Uryu, Kunihiro, Richter-Landsberg, Christiane, Welch, William, Sun, Eveline, Goldbaum, Olaf, Norris, Erin H., Pham, Chi-Tuan, Yazawa, Ikuru, Hilburger, Kristen, Micsenyi, Matthew, Giasson, Benoit I., Bonini, Nancy M., Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606542/
https://ncbi.nlm.nih.gov/pubmed/16507910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050770
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